Novel pneumococcal capsule type 33E results from the inactivation of glycosyltransferase WciE in vaccine type 33F.

Ganaie, Feroze A; Saad, Jamil S; Lo, Stephanie W; McGee, Lesley; van Tonder, Andries J; Hawkins, Paulina A; Calix, Juan J; Bentley, Stephen D; Nahm, Moon H

Ganaie, Feroze A; Saad, Jamil S; Lo, Stephanie W; McGee, Lesley; van Tonder, Andries J; Hawkins, Paulina A; Calix, Juan J; Bentley, Stephen D; Nahm, Moon H.

Afiliação

Ganaie FA; Division of Pulmonary/Allergy/Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Saad JS; Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Lo SW; Parasites and Microbes, Wellcome Sanger Institute, Cambridge, United Kingdom.
McGee L; Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
van Tonder AJ; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
Hawkins PA; Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; CDC Foundation, Atlanta, Georgia, USA.
Calix JJ; Division of Pulmonary/Allergy/Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Bentley SD; Parasites and Microbes, Wellcome Sanger Institute, Cambridge, United Kingdom.
Nahm MH; Division of Pulmonary/Allergy/Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address: mnahm@uabmc.edu.

J Biol Chem ; 299(9): 105085, 2023 09.

Article em En | MEDLINE | ID: mdl-37495106

Assuntos

Cápsulas Bacterianas; Genes Bacterianos; Infecções Pneumocócicas; Streptococcus pneumoniae; Transferases; Anticorpos Antibacterianos/imunologia; Projetos Piloto; Infecções Pneumocócicas/microbiologia; Infecções Pneumocócicas/prevenção & controle; Vacinas Pneumocócicas/classificação; Vacinas Pneumocócicas/imunologia; Polissacarídeos/química; Sorogrupo; Streptococcus pneumoniae/genética; Streptococcus pneumoniae/imunologia; Vacinas Conjugadas/classificação; Vacinas Conjugadas/imunologia; Cápsulas Bacterianas/química; Cápsulas Bacterianas/genética; Genes Bacterianos/genética; Genes Bacterianos/imunologia; Inativação Gênica; Transferases/genética; Transferases/metabolismo

Palavras-chave

Streptococcus pneumoniae; capsule polysaccharide; capsule type; serotype; vaccine; vaccine escape

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Streptococcus pneumoniae / Transferases / Cápsulas Bacterianas / Genes Bacterianos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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