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Trends in Stimulant and Sedative/Hypnotic Dispensing: An Exploratory Study.
Liou, Harris; Gentry, Melanie T; Leung, Jonathan G; Mara, Kristin C; Staab, Jeffrey P; Rummans, Teresa A.
Afiliação
  • Liou H; Mayo Clinic, Scottsdale, AZ, USA.
  • Gentry MT; Mayo Clinic, Rochester, MN, USA.
  • Leung JG; Mayo Clinic, Rochester, MN, USA.
  • Mara KC; Mayo Clinic, Rochester, MN, USA.
  • Staab JP; Mayo Clinic, Rochester, MN, USA.
  • Rummans TA; Mayo Clinic, Rochester, MN, USA.
J Atten Disord ; 27(13): 1512-1519, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37496458
OBJECTIVE: To investigate patterns and trends of co-prescriptions of stimulants and sedatives within the last 6 years at a tertiary care center. METHOD: Patients 18 years of age and older who were dispensed at least one stimulant prescription from an institutional pharmacy between 1/1/2015 and 7/1/2021 were included. Prescription data for any co-prescribed sedative/hypnotic were collected. RESULTS: Both the number of stimulant dispenses and the number of patients with stimulant dispenses increased significantly with yearly incidence rate ratios of 1.115 (95% CI [1.110, 1.119]) and 1.090 (95% CI [1.084, 1.096]), respectively. The number of patients with a stimulant dispensed who also had a benzodiazepine or "Z-drug" sedative-hypnotic dispensed at any point in the search timeframe increased significantly with incidence rate ratios of 1.077 and 1.092, respectively. The number of stimulant dispenses, number of patients with stimulant dispenses, and number of patients with a stimulant dispensed who also had both a benzodiazepine and Z-drug dispensed at any point in the search timeframe increased significantly more in Non-White than in White patients. CONCLUSIONS: The results confirm previous findings of increases in dispensing of stimulants over the past 6 years and report increased polypharmacy of stimulants and sedative-hypnotics.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article