A novel monospecific tetravalent IgG1-(scFv)<sub>2</sub> version shown enhanced neutralizing and Fc-mediated effector functions against SARS-CoV-2.

Gao, Zhang-Zhao; Jiao, Jing-Yu; Zhou, Ya-Qiong; Qi, Jian; Zhu, Shan-Shan; Xu, Jing-Ya; Nie, Lei; Wang, Hai-Bin

A novel monospecific tetravalent IgG1-(scFv)₂ version shown enhanced neutralizing and Fc-mediated effector functions against SARS-CoV-2.

Gao, Zhang-Zhao; Jiao, Jing-Yu; Zhou, Ya-Qiong; Qi, Jian; Zhu, Shan-Shan; Xu, Jing-Ya; Nie, Lei; Wang, Hai-Bin.

Afiliação

Gao ZZ; BioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Jiao JY; Hisun Biopharmaceutical Co., Ltd., Hangzhou, 311404 Zhejiang China.
Zhou YQ; BioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Qi J; Hisun Biopharmaceutical Co., Ltd., Hangzhou, 311404 Zhejiang China.
Zhu SS; BioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Xu JY; Hisun Biopharmaceutical Co., Ltd., Hangzhou, 311404 Zhejiang China.
Nie L; BioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Wang HB; Hisun Biopharmaceutical Co., Ltd., Hangzhou, 311404 Zhejiang China.

3 Biotech ; 13(8): 283, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37501919

Palavras-chave

COVID-19; Fc-mediated effector functions; Neutralizing; Tetravalent antibody

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article