DNA and protein methyltransferases inhibition by adenosine dialdehyde reduces the proliferation and migration of breast and lung cancer cells by downregulating autophagy.

Ghemrawi, Rose; Al Qassem, Aya; Ramadan, Azza; Aldulaymi, Raghad; Sammani, Nour; K Mousa, Walaa; Khair, Mostafa

Ghemrawi, Rose; Al Qassem, Aya; Ramadan, Azza; Aldulaymi, Raghad; Sammani, Nour; K Mousa, Walaa; Khair, Mostafa.

Afiliação

Ghemrawi R; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.
Al Qassem A; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.
Ramadan A; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.
Aldulaymi R; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.
Sammani N; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.
K Mousa W; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.
Khair M; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.

PLoS One ; 18(7): e0288791, 2023.

Article em En | MEDLINE | ID: mdl-37506102

Assuntos

Neoplasias da Mama; Neoplasias Pulmonares; Humanos; Feminino; Proteínas Metiltransferases/farmacologia; Células MCF-7; Metilação de DNA; Autofagia; DNA; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/genética; Proliferação de Células; Neoplasias da Mama/genética; Linhagem Celular Tumoral; Apoptose

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Neoplasias Pulmonares Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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