Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway.

Li, Qin; Li, Shuai; Fang, Jiankang; Yang, Chao; Zhao, Xia; Wang, Qing; Zhou, Wenshu; Zheng, Wenhua

Li, Qin; Li, Shuai; Fang, Jiankang; Yang, Chao; Zhao, Xia; Wang, Qing; Zhou, Wenshu; Zheng, Wenhua.

Afiliação

Li Q; Center of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Room 3057, Building E12, Taipa, Macau SAR 999078, China.
Li S; School of pharmacy, Hangzhou Medical College, Hangzhou 310059, China.
Fang J; Center of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Room 3057, Building E12, Taipa, Macau SAR 999078, China.
Yang C; Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Zhao X; Center of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Room 3057, Building E12, Taipa, Macau SAR 999078, China.
Wang Q; Center of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Room 3057, Building E12, Taipa, Macau SAR 999078, China.
Zhou W; Center of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Room 3057, Building E12, Taipa, Macau SAR 999078, China.
Zheng W; School of pharmacy, Hangzhou Medical College, Hangzhou 310059, China.

Molecules ; 28(14)2023 Jul 20.

Article em En | MEDLINE | ID: mdl-37513399

Assuntos

Artemisininas; Neuroblastoma; Doenças Neurodegenerativas; Fármacos Neuroprotetores; Doença de Parkinson; Ratos; Humanos; Camundongos; Animais; Doença de Parkinson/tratamento farmacológico; Doença de Parkinson/metabolismo; Sistema de Sinalização das MAP Quinases; Oxidopamina/efeitos adversos; Fármacos Neuroprotetores/uso terapêutico; Neuroproteção; Doenças Neurodegenerativas/tratamento farmacológico; RNA Guia de Sistemas CRISPR-Cas; Neuroblastoma/tratamento farmacológico; Apoptose; Artemisininas/metabolismo; Neurônios Dopaminérgicos

Palavras-chave

6-OHDA; MPTP/MPP+; Parkinson's disease; apoptosis; artemisinin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Fármacos Neuroprotetores / Doenças Neurodegenerativas / Artemisininas / Neuroblastoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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