[Knock-down of ROCK2 gene improves cognitive function and reduces neuronal apoptosis in AD mice by promoting mitochondrial fusion and inhibiting its division].

Guo, Minfang; Zhang, Huiyu; Zhang, Peijun; Yu, Jingwen; Meng, Tao; Li, Suyao; Song, Lijuan; Chai, Zhi; Yu, Jiezhong; Ma, Cungen

Guo, Minfang; Zhang, Huiyu; Zhang, Peijun; Yu, Jingwen; Meng, Tao; Li, Suyao; Song, Lijuan; Chai, Zhi; Yu, Jiezhong; Ma, Cungen.

Afiliação

Guo M; Institute of Brain Science, Shanxi Datong University, Datong 037009, China.
Zhang H; Institute of Brain Science, Shanxi Datong University, Datong 037009, China.
Zhang P; Institute of Brain Science, Shanxi Datong University, Datong 037009, China.
Yu J; Institute of Brain Science, Shanxi Datong University, Datong 037009, China.
Meng T; Institute of Brain Science, Shanxi Datong University, Datong 037009, China.
Li S; The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, China.
Song L; The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619; Department of Physiology, Shanxi Medical Univ
Chai Z; The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, China.
Yu J; Institute of Brain Science, Shanxi Datong University, Datong 037009; The Fourth People's Hospital of Datong, Datong 037008, China. *Corresponding authors, E-mail: sxdtyjz@qq.com.
Ma C; Institute of Brain Science, Shanxi Datong University, Datong 037009; The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Med

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi ; 39(8): 701-707, 2023 Aug.

Article em Zh | MEDLINE | ID: mdl-37515336

Assuntos

Doença de Alzheimer; Animais; Camundongos; Doença de Alzheimer/genética; Doença de Alzheimer/metabolismo; Doença de Alzheimer/patologia; Peptídeos beta-Amiloides/genética; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide; Apoptose/genética; Proteína X Associada a bcl-2; Caspase 3; Cognição; Modelos Animais de Doenças; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Dinâmica Mitocondrial/genética

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals Idioma: Zh Ano de publicação: 2023 Tipo de documento: Article

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PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals Idioma: Zh Ano de publicação: 2023 Tipo de documento: Article