Single-cell transcriptomics reveals prominent expression of IL-14, IL-18, and IL-32 in psoriasis.

Frost, Bennet; Schmidt, Maria; Klein, Benjamin; Loeffler-Wirth, Henry; Krohn, Knuth; Reidenbach, Timo; Binder, Hans; Stubenvoll, Antonia; Simon, Jan C; Saalbach, Anja; Kunz, Manfred

Frost, Bennet; Schmidt, Maria; Klein, Benjamin; Loeffler-Wirth, Henry; Krohn, Knuth; Reidenbach, Timo; Binder, Hans; Stubenvoll, Antonia; Simon, Jan C; Saalbach, Anja; Kunz, Manfred.

Afiliação

Frost B; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
Schmidt M; Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany.
Klein B; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
Loeffler-Wirth H; Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany.
Krohn K; Medical Faculty, Center for DNA Technologies, University of Leipzig, Leipzig, Germany.
Reidenbach T; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
Binder H; Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany.
Stubenvoll A; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
Simon JC; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
Saalbach A; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
Kunz M; Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.

Eur J Immunol ; 53(11): e2250354, 2023 11.

Article em En | MEDLINE | ID: mdl-37540729

Assuntos

Interleucina-18; Psoríase; Humanos; Camundongos; Animais; Interleucina-18/genética; Interleucina-18/metabolismo; Modelos Animais de Doenças; Transcriptoma; Psoríase/genética; Pele/patologia; Queratinócitos; Citocinas/metabolismo; Proteínas de Transporte Vesicular/genética; Proteínas de Transporte Vesicular/metabolismo

Palavras-chave

Chronic inflammation; Interleukins; Psoriasis; Single-cell transcriptomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Interleucina-18 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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