Dynamics of intestinal and intratumoral microbiome signatures in genetically engineered mice and human pancreatic ductal adenocarcinoma.

Pfisterer, Nina; Ammer-Herrmenau, Christoph; Antweiler, Kai; Küffer, Stefan; Ellenrieder, Volker; Neesse, Albrecht

Pfisterer, Nina; Ammer-Herrmenau, Christoph; Antweiler, Kai; Küffer, Stefan; Ellenrieder, Volker; Neesse, Albrecht.

Afiliação

Pfisterer N; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, 37075, Goettingen, Germany; Clinical Research Unit KFO5002, University Medical Center Goettingen, 37075, Goettingen, Germany.
Ammer-Herrmenau C; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, 37075, Goettingen, Germany; Clinical Research Unit KFO5002, University Medical Center Goettingen, 37075, Goettingen, Germany.
Antweiler K; Institute of Medical Statistics, University Medical Center Goettingen, 37073, Goettingen, Germany.
Küffer S; Institute of Pathology, University Medical Center Goettingen, 37075, Goettingen, Germany.
Ellenrieder V; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, 37075, Goettingen, Germany; Clinical Research Unit KFO5002, University Medical Center Goettingen, 37075, Goettingen, Germany.
Neesse A; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, 37075, Goettingen, Germany; Clinical Research Unit KFO5002, University Medical Center Goettingen, 37075, Goettingen, Germany. Electronic address: albrecht.neesse@med.uni-goettingen.de.

Pancreatology ; 23(6): 663-673, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37541802

Assuntos

Carcinoma Ductal Pancreático; Microbiota; Neoplasias Pancreáticas; Humanos; Camundongos; Animais; Hibridização in Situ Fluorescente; RNA Ribossômico 16S; Neoplasias Pancreáticas/genética; Neoplasias Pancreáticas/patologia; Carcinoma Ductal Pancreático/genética; Carcinoma Ductal Pancreático/patologia; Modelos Animais de Doenças; Microbiota/genética; Neoplasias Pancreáticas

Palavras-chave

KPC mouse model; Microbiome; Oxford nanopore technologies; PDAC; Pancreatic ductal adenocarcinoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Microbiota Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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