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Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.
Fancher, Ashley T; Hua, Yun; Close, David A; Xu, Wei; McDermott, Lee A; Strock, Christopher J; Santiago, Ulises; Camacho, Carlos J; Johnston, Paul A.
Afiliação
  • Fancher AT; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; Nucleus Global, 2 Ravinia Drive, Suite 605, Atlanta, GA 30346, USA.
  • Hua Y; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Close DA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Xu W; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • McDermott LA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; PsychoGenics Inc, 215 College Road, Paramus, NJ 07652, USA.
  • Strock CJ; Cyprotex US, 313 Pleasant Street, Watertown, MA 02472, USA.
  • Santiago U; Department of Computational and Systems Biology, School of Medicine, at the University of Pittsburgh, USA.
  • Camacho CJ; Department of Computational and Systems Biology, School of Medicine, at the University of Pittsburgh, USA.
  • Johnston PA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Hillman Cancer Center, Pittsburgh, PA 15232, USA. Electronic address: paj18@pitt.edu.
SLAS Discov ; 2023 Aug 06.
Article em En | MEDLINE | ID: mdl-37549772

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article