The Effects of a Curcumin Derivative and Osimertinib on Fatty Acyl Metabolism and Mitochondrial Functions in HCC827 Cells and Tumors.

Hsieh, Min-Tsang; Lee, Pei-Chih; Chiang, Yi-Ting; Lin, Hui-Yi; Lee, Der-Yen

Hsieh, Min-Tsang; Lee, Pei-Chih; Chiang, Yi-Ting; Lin, Hui-Yi; Lee, Der-Yen.

Afiliação

Hsieh MT; Drug Development Center, China Medical University, Taichung 406040, Taiwan.
Lee PC; School of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Chiang YT; Chinese Medicinal Research and Development Center, China Medical University Hospital, Taichung 40447, Taiwan.
Lin HY; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
Lee DY; Research Center for Cancer Biology, China Medical University, Taichung 406040, Taiwan.

Int J Mol Sci ; 24(15)2023 Jul 29.

Article em En | MEDLINE | ID: mdl-37569564

Assuntos

Curcumina; Neoplasias Pulmonares; Camundongos; Animais; Curcumina/farmacologia; Curcumina/uso terapêutico; Camundongos SCID; Neoplasias Pulmonares/metabolismo; Compostos de Anilina/farmacologia; Compostos de Anilina/uso terapêutico; Mitocôndrias/metabolismo; Inibidores de Proteínas Quinases/farmacologia; Linhagem Celular Tumoral; Resistencia a Medicamentos Antineoplásicos; Mutação

Palavras-chave

acylcarnitine; carnitine; fatty acyl metabolism; metabolomics; mitochondrial stress; tyrosine kinase inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Curcumina / Neoplasias Pulmonares Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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