Daily treatment with the dual orexin receptor antagonist DORA-12 during oxycodone abstinence decreases oxycodone conditioned reinstatement.

Illenberger, Jessica M; Flores-Ramirez, Francisco J; Pascasio, Glenn; Matzeu, Alessandra; Martin-Fardon, Rémi

Illenberger, Jessica M; Flores-Ramirez, Francisco J; Pascasio, Glenn; Matzeu, Alessandra; Martin-Fardon, Rémi.

Afiliação

Illenberger JM; The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA. Electronic address: jillenberger@scripps.edu.
Flores-Ramirez FJ; The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.
Pascasio G; The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.
Matzeu A; The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.
Martin-Fardon R; The Scripps Research Institute, 10550 North Torrey Pines Road, SR-107, La Jolla, CA, 92037, USA.

Neuropharmacology ; 239: 109685, 2023 11 15.

Article em En | MEDLINE | ID: mdl-37579870

Assuntos

Analgésicos Opioides; Oxicodona; Feminino; Ratos; Masculino; Animais; Oxicodona/farmacologia; Analgésicos Opioides/farmacologia; Antagonistas dos Receptores de Orexina/farmacologia; Ratos Sprague-Dawley; Ratos Wistar; Receptores de Orexina; Autoadministração

Palavras-chave

Dual orexin receptor antagonists; Oxycodone; Prescription opioid use disorder; Reinstatement

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxicodona / Analgésicos Opioides Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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