Preparation of eicosavalent triazolylsialoside-conjugated human serum albumin as a dual hemagglutinin/neuraminidase inhibitor and virion adsorbent for the prevention of influenza infection.

Li, Yang; Liu, Han-Yu; Yang, Ming-Jiang; Liu, Dong; Song, Jia-Qi; Lao, Zhiqi; Chen, Yue; Yang, Yang

Li, Yang; Liu, Han-Yu; Yang, Ming-Jiang; Liu, Dong; Song, Jia-Qi; Lao, Zhiqi; Chen, Yue; Yang, Yang.

Afiliação

Li Y; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin, 300457, China.
Liu HY; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin, 300457, China.
Yang MJ; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin, 300457, China.
Liu D; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin, 300457, China.
Song JQ; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin, 300457, China.
Lao Z; Department of Medical Laboratory, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen, Guangdong, 518020, China; Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, 510632, China. Electronic address: jimlao@126.
Chen Y; Department of Medical Laboratory, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen, Guangdong, 518020, China. Electronic address: chenyue_dr@163.com.
Yang Y; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin, 300457, China. Electronic address: yyang@tust.edu.cn.

Carbohydr Res ; 532: 108918, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37586142

Assuntos

Influenza Humana; Animais; Cães; Humanos; Antivirais/química; Células Endoteliais/metabolismo; Glicoproteínas de Hemaglutininação de Vírus da Influenza/metabolismo; Hemaglutininas/metabolismo; Células Madin Darby de Rim Canino; Ácido N-Acetilneuramínico/metabolismo; Neuraminidase/metabolismo; Albumina Sérica Humana; Proteínas Virais/antagonistas & inibidores; Proteínas Virais/química; Proteínas Virais/metabolismo; Vírion/metabolismo

Palavras-chave

Human serum albumin conjugate; Influenza hemagglutinin/neuraminidase inhibitor; Multivalent sialoside; Surface plasmon resonance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Influenza Humana Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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