Xiao-qing-long-tang ameliorates OVA-induced allergic rhinitis by inhibiting ILC2s through the IL-33/ST2 and JAK/STAT pathways.

Zhang, Jia-Jun; He, Xue-Cheng; Zhou, Min; Liu, Qin-Dong; Xu, Wei-Zhen; Yan, Ya-Jie; Ruan, Yan

Zhang, Jia-Jun; He, Xue-Cheng; Zhou, Min; Liu, Qin-Dong; Xu, Wei-Zhen; Yan, Ya-Jie; Ruan, Yan.

Afiliação

Zhang JJ; The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Department of Otorhinolaryngology, the Second People's Hospital of Foshan, Affiliated Foshan Hospital of Southern Medical University, Foshan, Guangdong Province, 528099, China.
He XC; The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Zhou M; Otorhinolaryngology Department, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Liu QD; The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Xu WZ; The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Yan YJ; Otorhinolaryngology Department, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, 510405, China. Electronic address: yajieyan50008@gzucm.edu.cn.
Ruan Y; Otorhinolaryngology Department, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, 510405, China. Electronic address: ry0722@gzucm.edu.cn.

Phytomedicine ; 119: 155012, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37586158

Assuntos

Imunidade Inata; Rinite Alérgica; Animais; Camundongos; Ovalbumina; Proteína 1 Semelhante a Receptor de Interleucina-1/metabolismo; Janus Quinases/metabolismo; Interleucina-33/metabolismo; Linfócitos; Transdução de Sinais; Fatores de Transcrição STAT/metabolismo; Rinite Alérgica/induzido quimicamente; Rinite Alérgica/tratamento farmacológico; Citocinas/metabolismo; Modelos Animais de Doenças; Camundongos Endogâmicos BALB C

Palavras-chave

Allergic rhinitis; IL-33/ST2 signaling; ILC2s; JAK/STAT pathway; Xiao-qing-long-tang

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rinite Alérgica / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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