Deciphering the landscape of transcriptional heterogeneity across cancer.

Jones, Thomas P; McGranahan, Nicholas

Jones, Thomas P; McGranahan, Nicholas.

Afiliação

Jones TP; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
McGranahan N; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Electronic address: nicholas.mcgranahan.10@ucl.ac.uk.

Cancer Cell ; 41(9): 1548-1550, 2023 09 11.

Article em En | MEDLINE | ID: mdl-37595585

RESUMO

By integrating scRNA-seq datasets across 77 studies and 24 cancer types, in Nature, Gavish et al. uncover recurrent patterns of gene expression that explain a significant proportion of transcriptomic heterogeneity observed in cancer and explore their functional significance.

Assuntos

Neoplasias; Humanos; Neoplasias/genética; Perfilação da Expressão Gênica; Transcriptoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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