Distinct mutational processes shape selection of MHC class I and class II mutations across primary and metastatic tumors.

Mumphrey, Michael B; Hosseini, Noshad; Parolia, Abhijit; Geng, Jie; Zou, Weiping; Raghavan, Malini; Chinnaiyan, Arul; Cieslik, Marcin

Mumphrey, Michael B; Hosseini, Noshad; Parolia, Abhijit; Geng, Jie; Zou, Weiping; Raghavan, Malini; Chinnaiyan, Arul; Cieslik, Marcin.

Afiliação

Mumphrey MB; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Hosseini N; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Parolia A; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
Geng J; Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI 48109, USA.
Zou W; Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI 48109, USA; Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan, Ann Arbor, MI 48109, USA; University of Michigan Rogel Cancer Center, Ann Arbor, MI 48109, USA.
Raghavan M; Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI 48109, USA.
Chinnaiyan A; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Urology
Cieslik M; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; University of Michiga

Cell Rep ; 42(8): 112965, 2023 08 29.

Article em En | MEDLINE | ID: mdl-37597185

Assuntos

Antígenos de Histocompatibilidade Classe I; Neoplasias; Humanos; Antígenos de Histocompatibilidade Classe I/metabolismo; Antígenos HLA; Neoplasias/genética; Linfócitos T; Antígenos de Histocompatibilidade Classe II/genética; Mutação/genética

Palavras-chave

CP: Cancer; CP: Immunology; HLA; MHC; cancer; evolution; genomics; immunogenetics; selection; somatic mutations

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos de Histocompatibilidade Classe I / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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