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Molecular overlay-guided design of new CDK2 inhibitor thiazepinopurines: Synthesis, anticancer, and mechanistic investigations.
Husseiny, Ebtehal M; Abulkhair, Hamada S; Saleh, Asmaa; Altwaijry, Najla; Zidan, Riham A; Abdulrahman, Fatma G.
Afiliação
  • Husseiny EM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City 11754, Cairo, Egypt.
  • Abulkhair HS; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Nasr City 11884, Cairo, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Horus University-Egypt, International Coastal Road, New Damietta 34518, Egypt.
  • Saleh A; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. Electronic address: asali@pnu.edu.sa.
  • Altwaijry N; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
  • Zidan RA; Department of Biochemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
  • Abdulrahman FG; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City 11754, Cairo, Egypt.
Bioorg Chem ; 140: 106789, 2023 11.
Article em En | MEDLINE | ID: mdl-37611530
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazepinas Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazepinas Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article