Design and characterization of a novel tumor-homing cell-penetrating peptide for drug delivery in TGFBR3 high-expressing tumors.

Wu, Yi-Jie; Lei, Jin; Zhao, Jian; Cao, Xue-Wei; Wang, Fu-Jun

Wu, Yi-Jie; Lei, Jin; Zhao, Jian; Cao, Xue-Wei; Wang, Fu-Jun.

Afiliação

Wu YJ; Department of Applied Biology, East China University of Science and Technology, Shanghai, China.
Lei J; Department of Applied Biology, East China University of Science and Technology, Shanghai, China.
Zhao J; Department of Applied Biology, East China University of Science and Technology, Shanghai, China.
Cao XW; ECUST-FONOW Joint Research Center for Innovative Medicines, East China University of Science and Technology, Shanghai, China.
Wang FJ; Department of Applied Biology, East China University of Science and Technology, Shanghai, China.

Chem Biol Drug Des ; 102(6): 1421-1434, 2023 12.

Article em En | MEDLINE | ID: mdl-37620132

Assuntos

Peptídeos Penetradores de Células; Masculino; Humanos; Peptídeos Penetradores de Células/química; Sistemas de Liberação de Medicamentos; Receptores de Fatores de Crescimento Transformadores beta/genética; Receptores de Fatores de Crescimento Transformadores beta/metabolismo; Proteoglicanas/genética; Proteoglicanas/metabolismo; Linhagem Celular Tumoral

Palavras-chave

Type III transforming growth factor ß receptor (TGFBR3); apoptosis; bone morphogenetic protein 4 (BMP4); trichosanthin (TCS); tumor-homing cell-penetrating peptide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Penetradores de Células Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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