Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes.

Froberg, John E; Durak, Omer; Macklis, Jeffrey D

Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes.

Froberg, John E; Durak, Omer; Macklis, Jeffrey D.

Afiliação

Froberg JE; Department of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Durak O; Department of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Macklis JD; Department of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA. Electronic address: jeffreymacklis@fas.harvard.edu.

Cell Rep ; 42(9): 112995, 2023 09 26.

Article em En | MEDLINE | ID: mdl-37624698

Assuntos

Axônios; Neurônios; Fases de Leitura Aberta/genética; Neurônios/metabolismo; Axônios/metabolismo; Ribossomos/genética; Ribossomos/metabolismo; Corpo Caloso/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Biossíntese de Proteínas

Palavras-chave

CP: Neuroscience; Ribo-seq; callosal projection neurons; cortical development; mRNA translation; molecular controls over neuronal diversity; ribosome; ribosome profiling; subcerebral projection neurons; translational regulation; upstream open reading frame (uORF)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Axônios / Neurônios Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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