Practicality of non-invasive glucagon-loaded dissolving microneedle for life-saving treatment of severe hypoglycemia in a diabetic rat model.

Wang, Xuejiao; Ma, Yinling; Qi, Xiaodan; Ruan, Xi; Cao, Deying; Zhao, Feng

Wang, Xuejiao; Ma, Yinling; Qi, Xiaodan; Ruan, Xi; Cao, Deying; Zhao, Feng.

Afiliação

Wang X; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China.
Ma Y; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China; National Clinical Drug Monitoring Center, Department of Pharmacy, Hebei Province General Center, Shijiazhuang 050051, China.
Qi X; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China.
Ruan X; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China.
Cao D; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China. Electronic address: deyingcao@hebmu.edu.cn.
Zhao F; School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China. Electronic address: zhaofeng@hebmu.edu.cn.

Int J Pharm ; 644: 123340, 2023 Sep 25.

Article em En | MEDLINE | ID: mdl-37625601

Assuntos

Diabetes Mellitus; Hipoglicemia; Animais; Ratos; Glucagon; Hipoglicemia/induzido quimicamente; Hipoglicemia/tratamento farmacológico; Hipoglicemiantes; Pele

Palavras-chave

Circular dichroism; Diabetes; Dissolving microneedle; Glucagon; Hyperglycemic therapy; Hypoglycemia; Preparation process

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus / Hipoglicemia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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