Sodium acetate abates lead-induced sexual dysfunction by upregulating testosterone-dependent eNOS/NO/cGMP signaling and activating Nrf2/HO-1 in male Wistar rat.

Besong, E E; Ashonibare, P J; Akhigbe, T M; Obimma, J N; Akhigbe, R E

Besong, E E; Ashonibare, P J; Akhigbe, T M; Obimma, J N; Akhigbe, R E.

Afiliação

Besong EE; Department of Physiology, Faculty of Basic Medical Sciences, Ebonyi State University, Abakaliki, Nigeria.
Ashonibare PJ; Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
Akhigbe TM; Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Osun State, Nigeria.
Obimma JN; Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Osun State, Nigeria.
Akhigbe RE; Breeding and Plant Genetics Unit, Department of Agronomy, Osun State University, Osogbo, Osun State, Nigeria.

Naunyn Schmiedebergs Arch Pharmacol ; 397(2): 1233-1243, 2024 02.

Article em En | MEDLINE | ID: mdl-37658211

Assuntos

Chumbo; Testosterona; Ratos; Masculino; Animais; Ratos Wistar; Chumbo/farmacologia; Fator 2 Relacionado a NF-E2/metabolismo; Acetato de Sódio/farmacologia; Acetilcolinesterase; Antioxidantes/farmacologia; Estresse Oxidativo

Palavras-chave

Androgen; Erectogenic enzymes; Heavy metals; Oxidative stress; Sex act; Short-chain fatty acids

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testosterona / Chumbo Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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