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Testing and treatment for malaria elimination: a systematic review.
Newby, Gretchen; Cotter, Chris; Roh, Michelle E; Harvard, Kelly; Bennett, Adam; Hwang, Jimee; Chitnis, Nakul; Fine, Sydney; Stresman, Gillian; Chen, Ingrid; Gosling, Roly; Hsiang, Michelle S.
Afiliação
  • Newby G; Malaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco (UCSF), 550 16th Street, San Francisco, CA, 94143, USA.
  • Cotter C; Malaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco (UCSF), 550 16th Street, San Francisco, CA, 94143, USA.
  • Roh ME; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
  • Harvard K; Malaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco (UCSF), 550 16th Street, San Francisco, CA, 94143, USA.
  • Bennett A; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, USA.
  • Hwang J; Malaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco (UCSF), 550 16th Street, San Francisco, CA, 94143, USA.
  • Chitnis N; Malaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco (UCSF), 550 16th Street, San Francisco, CA, 94143, USA.
  • Fine S; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, USA.
  • Stresman G; PATH, Seattle, WA, USA.
  • Chen I; Malaria Branch, Centers for Disease Control and Prevention, U.S. President's Malaria Initiative, Atlanta, GA, USA.
  • Gosling R; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
  • Hsiang MS; University of Basel, Basel, Switzerland.
Malar J ; 22(1): 254, 2023 Sep 03.
Article em En | MEDLINE | ID: mdl-37661286
ABSTRACT

BACKGROUND:

Global interest in malaria elimination has prompted research on active test and treat (TaT) strategies.

METHODS:

A systematic review and meta-analysis were conducted to assess the effectiveness of TaT strategies to reduce malaria transmission.

RESULTS:

A total of 72 empirical research and 24 modelling studies were identified, mainly focused on proactive mass TaT (MTaT) and reactive case detection (RACD) in higher and lower transmission settings, respectively. Ten intervention studies compared MTaT to no MTaT and the evidence for impact on malaria incidence was weak. No intervention studies compared RACD to no RACD. Compared to passive case detection (PCD) alone, PCD + RACD using standard diagnostics increased infection detection 52.7% and 11.3% in low and very low transmission settings, respectively. Using molecular methods increased this detection of infections by 1.4- and 1.1-fold, respectively.

CONCLUSION:

Results suggest MTaT is not effective for reducing transmission. By increasing case detection, surveillance data provided by RACD may indirectly reduce transmission by informing coordinated responses of intervention targeting.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Malária Tipo de estudo: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Malária Tipo de estudo: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article