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Safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of aficamten in healthy Chinese participants: a randomized, double-blind, placebo-controlled, phase 1 study.
Zhao, Xue; Liu, Hongzhong; Tian, Wei; Fang, Ligang; Yu, Mengyang; Wu, Xiaofei; Liu, Aijing; Wan, Ruijie; Li, Li; Luo, Jinghui; Li, Yuqiong; Liu, Bo; He, Yu; Chen, Xiaowen; Li, Yuan; Xu, Donghong; Wang, Hongyun; Han, Xiaohong.
Afiliação
  • Zhao X; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Liu H; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Tian W; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Fang L; Internal Medicine-Cardiovascular Department, Peking Union Medical College Hospital, Beijing, China.
  • Yu M; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Wu X; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Liu A; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Wan R; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Li L; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Luo J; Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, China.
  • Li Y; Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, China.
  • Liu B; Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, China.
  • He Y; Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, China.
  • Chen X; Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, China.
  • Li Y; Ji Xing Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, China.
  • Xu D; Cytokinetics, Incorporated, South San Francisco, CA, United States.
  • Wang H; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
  • Han X; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Beijing, China.
Front Pharmacol ; 14: 1227470, 2023.
Article em En | MEDLINE | ID: mdl-37680714
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Ano de publicação: 2023 Tipo de documento: Article