Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis.

Jalan-Sakrikar, Nidhi; Anwar, Abid; Yaqoob, Usman; Gan, Can; Lagnado, Anthony B; Wixom, Alexander Q; Jurk, Diana; Huebert, Robert C

Jalan-Sakrikar, Nidhi; Anwar, Abid; Yaqoob, Usman; Gan, Can; Lagnado, Anthony B; Wixom, Alexander Q; Jurk, Diana; Huebert, Robert C.

Afiliação

Jalan-Sakrikar N; Division of Gastroenterology and Hepatology.
Anwar A; Gastroenterology Research Unit.
Yaqoob U; Center for Cell Signaling in Gastroenterology, and.
Gan C; Division of Gastroenterology and Hepatology.
Lagnado AB; Gastroenterology Research Unit.
Wixom AQ; Division of Gastroenterology and Hepatology.
Jurk D; Gastroenterology Research Unit.
Huebert RC; Division of Gastroenterology and Hepatology.

JCI Insight ; 8(20)2023 Oct 23.

Article em En | MEDLINE | ID: mdl-37707950

Assuntos

Colangite Esclerosante; Humanos; Animais; Camundongos; Colangite Esclerosante/genética; Colangite Esclerosante/metabolismo; Colangite Esclerosante/patologia; Fígado/metabolismo; Ductos Biliares/metabolismo; Fibrose; Telômero

Palavras-chave

Cellular senescence; Fibrosis; Gastroenterology; Hepatology; Telomeres

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colangite Esclerosante Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google