[Epidemiological characteristics of mpox epidemic in Guangzhou].
Zhonghua Liu Xing Bing Xue Za Zhi
; 44(9): 1421-1425, 2023 Sep 10.
Article
em Zh
| MEDLINE
| ID: mdl-37743276
ABSTRACT
Objective:
To understand the epidemiological characteristics of mpox epidemic in Guangzhou and provide scientific evidence for the prevention and control of the disease.Methods:
Based on the mpox surveillance system in Guangzhou, suspected mpox cases with fever and rash were reported by local hospitals at all levels to centers for disease control and prevention in Guangzhou for sampling, investigation and diagnosis. Descriptive epidemiological analysis was conducted on the clinical characteristics and treatment of the mpox cases and positive detection rate reported in Guangzhou as of 2400 on June 23. Whole genome sequencing of the virus isolates was performed using Illumina Miniseq high-throughput sequencing platform.Results:
The first mpox case in Guangzhou was reported on June 10 in 2023. As of 2400 on June 23, a total of 25 confirmed mpox cases were reported. All the mpox cases were men with a M(Q1,Q3) of 32 (26, 36) years, the majority of the cases were MSM (96.0%). The main clinical features were rash (100.0%, 25/25), lymphadenectasis (100.0%, 25/25) and fever (52.0%, 13/25). Rash usually occurred near the genitals (88.0%, 22/25). The close contacts, mainly family members (40.4%, 23/57), showed no similar symptoms, such as fever or rash. The positive rate of mpox virus in household environment samples was 30.5%. The analyses on 3 complete gene sequences of mpox virus indicated that the strains belonged to West African type â ¡b clade, B.1.3 lineage.Conclusions:
Hidden transmission of mpox virus had occurred in MSM in Guangzhou. However, the size of affected population is relatively limited, and the possibility of wide spread of the virus is low.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mpox
/
Exantema
/
Epidemias
/
Minorias Sexuais e de Gênero
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article