Development of a New Cell-Based AP-1 Gene Reporter Potency Assay for Anti-Anthrax Toxin Therapeutics.

Ouyang, Weiming; Xie, Tao; Fang, Hui; Frucht, David M

Ouyang, Weiming; Xie, Tao; Fang, Hui; Frucht, David M.

Afiliação

Ouyang W; Division of Biotechnology Review and Research II, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
Xie T; Division of Biotechnology Review and Research II, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
Fang H; Division of Biotechnology Review and Research II, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
Frucht DM; Division of Biotechnology Review and Research II, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.

Toxins (Basel) ; 15(9)2023 08 28.

Article em En | MEDLINE | ID: mdl-37755954

Assuntos

Antraz; Toxinas Bacterianas; Humanos; Fator de Transcrição AP-1/genética; Toxinas Bacterianas/genética; Exotoxinas

Palavras-chave

AP-1; Bacillus anthracis; anthrax; edema toxin; lethal toxin; protective antigen; reporter assay

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Antraz Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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