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Biomarkers for Kidney-Transplant Rejection: A Short Review Study.
Sharaby, Israa; Alksas, Ahmed; Abou El-Ghar, Mohamed; Eldeeb, Mona; Ghazal, Mohammed; Gondim, Dibson; El-Baz, Ayman.
Afiliação
  • Sharaby I; Bioengineering Department, University of Louisville, Louisville, KY 40292, USA.
  • Alksas A; Bioengineering Department, University of Louisville, Louisville, KY 40292, USA.
  • Abou El-Ghar M; Radiology Department, Urology and Nephrology Center, Mansoura University, Mansoura 35516, Egypt.
  • Eldeeb M; Radiology Department, Urology and Nephrology Center, Mansoura University, Mansoura 35516, Egypt.
  • Ghazal M; Electrical, Computer, and Biomedical Engineering Department, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.
  • Gondim D; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY 40202, USA.
  • El-Baz A; Bioengineering Department, University of Louisville, Louisville, KY 40292, USA.
Biomedicines ; 11(9)2023 Aug 31.
Article em En | MEDLINE | ID: mdl-37760879
Kidney transplantation is the preferred treatment for end-stage renal failure, but the limited availability of donors and the risk of immune rejection pose significant challenges. Early detection of acute renal rejection is a critical step to increasing the lifespan of the transplanted kidney. Investigating the clinical, genetic, and histopathological markers correlated to acute renal rejection, as well as finding noninvasive markers for early detection, is urgently needed. It is also crucial to identify which markers are associated with different types of acute renal rejection to manage treatment effectively. This short review summarizes recent studies that investigated various markers, including genomics, histopathology, and clinical markers, to differentiate between different types of acute kidney rejection. Our review identifies the markers that can aid in the early detection of acute renal rejection, potentially leading to better treatment and prognosis for renal-transplant patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Screening_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Screening_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article