The Possibility of Using Fruit-Bearing Plants of Temperate Climate in the Treatment and Prevention of Diabetes.

Diabetes mellitus is one of the most dangerous metabolic diseases. The incidence of this disease continues to increase and is often associated with severe complications. Plants and natural plant products with a healing effect have been successfully used in the treatment of many disease entities since the beginning of the history of herbalism and medicine. At present, great emphasis is placed on the biodiversity of crops and the replacement of the monoculture production system of popular temperate climate plants, such as apple, pear, plum, and vine, with alternative fruit species. Very promising fruit plants are Cornelian cherry (Cornus mas); mulberry (Morus alba); bird cherry (Prunus padus); sour cherry (Prunus cerasus); plants of the genus Amelanchier, Sorbus, and Crategus; medlar (Mespilus germanica); quince (Cydonia oblonga); plants of the genus Vaccinium; and wild roses. When promoting the cultivation of alternative fruit-bearing plants, it is worth emphasizing their beneficial effects on health. This systematic review indicates that the antidiabetic effect of various parts of fruit plants is attributed to the presence of polyphenols, especially anthocyanins, which have different mechanisms of antidiabetic action and can be used in the treatment of diabetes and various complications associated with this disease.