Mechanistic Skin Modeling of Plasma Concentrations of Sunscreen Active Ingredients Following Facial Application.

Hamadeh, Abdullah; Nash, J F; Bialk, Heidi; Styczynski, Peter; Troutman, John; Edginton, Andrea

Hamadeh, Abdullah; Nash, J F; Bialk, Heidi; Styczynski, Peter; Troutman, John; Edginton, Andrea.

Afiliação

Hamadeh A; School of Pharmacy, University of Waterloo, Kitchener, ON N2G 1C5, Canada; Systems In Silico Ltd., Waterloo, ON, Canada.
Nash JF; The Procter & Gamble Company, Mason, OH 45040, USA.
Bialk H; The Estée Lauder Companies Inc., Melville, NY 11747, USA.
Styczynski P; The Procter & Gamble Company, Mason, OH 45040, USA.
Troutman J; The Procter & Gamble Company, Mason, OH 45040, USA.
Edginton A; School of Pharmacy, University of Waterloo, Kitchener, ON N2G 1C5, Canada; Design2Code Inc., Waterloo, ON, Canada. Electronic address: aedginto@uwaterloo.ca.

J Pharm Sci ; 113(3): 806-825, 2024 03.

Article em En | MEDLINE | ID: mdl-37769994

Assuntos

Acrilatos; Benzimidazóis; Benzofenonas; Cinamatos; Propiofenonas; Salicilatos; Ácidos Sulfônicos; Protetores Solares; Raios Ultravioleta; Humanos; Teorema de Bayes; Raios Ultravioleta/efeitos adversos

Palavras-chave

Dermal; IVIVE; Mechanistic; Modeling; Pharmacokinetics; Sunscreen; UV filters

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propiofenonas / Ácidos Sulfônicos / Protetores Solares / Raios Ultravioleta / Benzimidazóis / Benzofenonas / Acrilatos / Salicilatos / Cinamatos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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