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Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial.
Broome, Catherine M; McDonald, Vickie; Miyakawa, Yoshitaka; Carpenedo, Monica; Kuter, David J; Al-Samkari, Hanny; Bussel, James B; Godar, Marie; Ayguasanosa, Jaume; De Beuf, Kristof; Rodeghiero, Francesco; Michel, Marc; Newland, Adrian.
Afiliação
  • Broome CM; Lombardi Cancer Center, Division of Hematology, Georgetown University, Washington, DC, USA. Electronic address: catherine.m.broome@gunet.georgetown.edu.
  • McDonald V; Department of Clinical Haematology, Barts Health NHS Trust, London, UK.
  • Miyakawa Y; Department of Hematology, Saitama Medical University Hospital, Saitama, Japan.
  • Carpenedo M; Hematology and Transplant Unit, UOC Hematology and Transplant Unit Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
  • Kuter DJ; Hematology Division, Massachusetts General Hospital, Boston, MA, USA.
  • Al-Samkari H; Hematology Division, Massachusetts General Hospital, Boston, MA, USA.
  • Bussel JB; Division of Hematology and Medical Oncology and Division of Pediatric Hematology and Oncology, Weill Cornell Medical College, New York, NY, USA.
  • Godar M; argenx, Ghent, Belgium.
  • Ayguasanosa J; argenx, Ghent, Belgium.
  • De Beuf K; argenx, Ghent, Belgium.
  • Rodeghiero F; Haematology Project Foundation, Department of Haematology, S Bortolo Hospital, Vicenza, Italy.
  • Michel M; Department of Internal Medicine, National Reference Center for Immune Cytopenias, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Est Créteil, Créteil, France.
  • Newland A; Centre for Haematology, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Lancet ; 402(10413): 1648-1659, 2023 11 04.
Article em En | MEDLINE | ID: mdl-37778358
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombocitopenia / Púrpura Trombocitopênica Idiopática Tipo de estudo: Clinical_trials Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombocitopenia / Púrpura Trombocitopênica Idiopática Tipo de estudo: Clinical_trials Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article