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Isogenic pairs of induced-pluripotent stem-derived endothelial cells identify DYRK1A/PPARG/EGR1 pathway is responsible for Down syndrome-associated pulmonary hypertension.
Suginobe, Hidehiro; Ishida, Hidekazu; Ishii, Yoichiro; Ueda, Kazutoshi; Yoshihara, Chika; Ueyama, Atsuko; Wang, Renjie; Tsuru, Hirofumi; Hashimoto, Kazuhisa; Hirose, Masaki; Ishii, Ryo; Narita, Jun; Kitabatake, Yasuji; Ozono, Keiichi.
Afiliação
  • Suginobe H; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Ishida H; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Ishii Y; Department of Pediatric Cardiology, Osaka Children's and Women's Hospital, 840 Murodohcho, Izumi, Osaka 594-1101, Japan.
  • Ueda K; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Yoshihara C; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Ueyama A; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Wang R; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Tsuru H; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Hashimoto K; Department of Pediatrics, Niigata University School of Medicine, 1-757 Asahimachi-dori, chuo-ku, Niigata 951-8510, Japan.
  • Hirose M; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Ishii R; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Narita J; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Kitabatake Y; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Ozono K; Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Hum Mol Genet ; 33(1): 78-90, 2023 Dec 12.
Article em En | MEDLINE | ID: mdl-37792788
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Down / Células-Tronco Pluripotentes Induzidas / Hipertensão Arterial Pulmonar / Hipertensão Pulmonar Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Down / Células-Tronco Pluripotentes Induzidas / Hipertensão Arterial Pulmonar / Hipertensão Pulmonar Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article