The transcriptome landscape of 3D-cultured placental trophoblasts reveals activation of TLR2 and TLR3/7 in response to low <i>Trypanosoma cruzi</i> parasite exposure.

Silberstein, Erica; Chung, Charles C; Debrabant, Alain

The transcriptome landscape of 3D-cultured placental trophoblasts reveals activation of TLR2 and TLR3/7 in response to low Trypanosoma cruzi parasite exposure.

Silberstein, Erica; Chung, Charles C; Debrabant, Alain.

Afiliação

Silberstein E; Laboratory of Emerging Pathogens, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.
Chung CC; High-performance Integrated Virtual Environment Team, Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.
Debrabant A; Laboratory of Emerging Pathogens, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.

Front Microbiol ; 14: 1256385, 2023.

Article em En | MEDLINE | ID: mdl-37799608

Palavras-chave

3D-trophoblasts; Toll-like receptors; Trypanosoma cruzi; congenital Chagas disease; resistance to infection; transcriptome analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article