Investigating the biosynthesis and metabolism of 11ß-hydroxyandrostenedione.

Swart, Amanda C; van Rooyen, Desmaré; du Toit, Therina

Swart, Amanda C; van Rooyen, Desmaré; du Toit, Therina.

Afiliação

Swart AC; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa; Department of Chemistry, Stellenbosch University, Stellenbosch, South Africa. Electronic address: acswart@sun.ac.za.
van Rooyen D; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.
du Toit T; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.

Methods Enzymol ; 689: 387-431, 2023.

Article em En | MEDLINE | ID: mdl-37802580

Assuntos

Androstenodiona; Espectrometria de Massas em Tandem; Humanos; Androstenodiona/química; Androstenodiona/metabolismo; DNA Recombinante/metabolismo; Esteroides/química; Esteroides/metabolismo; Redes e Vias Metabólicas

Palavras-chave

11-ketotestosterone (11KT); 11ß-hydroxyandrosterone (11OHAST); 11ß-hydroxyetiocholanolone; Adrenal cytochrome P450; Androgen excess; LCMS method development and validation; Liquid chromatographymass spectrometry (LCMS); Qualifier:quantifier; Steroid extraction; Steroid mass transitions (MRM)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Androstenodiona Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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