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GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.
Wright, Shane C; Motso, Aikaterini; Koutsilieri, Stefania; Beusch, Christian M; Sabatier, Pierre; Berghella, Alessandro; Blondel-Tepaz, Élodie; Mangenot, Kimberley; Pittarokoilis, Ioannis; Sismanoglou, Despoina-Christina; Le Gouill, Christian; Olsen, Jesper V; Zubarev, Roman A; Lambert, Nevin A; Hauser, Alexander S; Bouvier, Michel; Lauschke, Volker M.
Afiliação
  • Wright SC; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden. shane.wright@ki.se.
  • Motso A; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, H3T 1J4, Canada. shane.wright@ki.se.
  • Koutsilieri S; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC, H3T 1J4, Canada. shane.wright@ki.se.
  • Beusch CM; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Sabatier P; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Berghella A; Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden.
  • Blondel-Tepaz É; Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden.
  • Mangenot K; Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
  • Pittarokoilis I; Department of Surgical Sciences, Uppsala University, Uppsala, 75185, Sweden.
  • Sismanoglou DC; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Le Gouill C; Faculty of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Teramo, 64100, Italy.
  • Olsen JV; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, H3T 1J4, Canada.
  • Zubarev RA; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC, H3T 1J4, Canada.
  • Lambert NA; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, H3T 1J4, Canada.
  • Hauser AS; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC, H3T 1J4, Canada.
  • Bouvier M; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Lauschke VM; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Nat Commun ; 14(1): 6243, 2023 10 09.
Article em En | MEDLINE | ID: mdl-37813859
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Incretinas / Receptor do Peptídeo Semelhante ao Glucagon 1 Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Incretinas / Receptor do Peptídeo Semelhante ao Glucagon 1 Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article