The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least.
Endocrinol Metab (Seoul)
; 38(5): 493-503, 2023 10.
Article
em En
| MEDLINE
| ID: mdl-37816498
ABSTRACT
The growing recognition of mitochondria's crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for enabling adipose tissue plasticity in response to various metabolic cues. Effective control of mitochondrial function at the cellular level, not only in thermogenic brown and beige adipocytes but also in energy-storing white adipocytes, exerts a profound influence on adipose homeostasis. Furthermore, mitochondria play a pivotal role in intercellular communication within adipose tissue via production of metabolites with signaling properties. A more comprehensive understanding of mitochondrial regulation within white adipocytes will empower the development of targeted and efficacious strategies to enhance adipose function, leading to advancements in overall metabolic health.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tecido Adiposo
/
Adipócitos Brancos
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article