Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton.

Polino, Alexander J; Ng, Xue Wen; Rooks, Rebecca; Piston, David W

Polino, Alexander J; Ng, Xue Wen; Rooks, Rebecca; Piston, David W.

Afiliação

Polino AJ; Department of Cell Biology & Physiology, Washington University School of Medicine, St Louis, Missouri, USA.
Ng XW; Department of Cell Biology & Physiology, Washington University School of Medicine, St Louis, Missouri, USA.
Rooks R; Department of Cell Biology & Physiology, Washington University School of Medicine, St Louis, Missouri, USA.
Piston DW; Department of Cell Biology & Physiology, Washington University School of Medicine, St Louis, Missouri, USA. Electronic address: piston@wustl.edu.

J Biol Chem ; 299(11): 105334, 2023 Nov.

Article em En | MEDLINE | ID: mdl-37827287

Assuntos

Citoesqueleto de Actina; Actinas; Secreção de Insulina; Células Secretoras de Insulina; Animais; Citoesqueleto de Actina/metabolismo; Actinas/metabolismo; Glucose/farmacologia; Insulina/metabolismo; Células Secretoras de Insulina/metabolismo

Palavras-chave

F-actin; beta cell; cell cortex; depolymerization; hormone secretion; islet of Langerhans; pancreatic islet; polymerization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citoesqueleto de Actina / Actinas / Células Secretoras de Insulina / Secreção de Insulina Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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