How Does cGAS Avoid Sensing Self-DNA under Normal Physiological Conditions?

Zheng, Wangli; Chen, Nanhua; Meurens, François; Zheng, Wanglong; Zhu, Jianzhong

Zheng, Wangli; Chen, Nanhua; Meurens, François; Zheng, Wanglong; Zhu, Jianzhong.

Afiliação

Zheng W; College Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Chen N; Joint International Research Laboratory of Agriculture and Agri-Product Safety, Yangzhou University, Yangzhou 225009, China.
Meurens F; Comparative Medicine Research Institute, Yangzhou University, Yangzhou 225009, China.
Zheng W; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.
Zhu J; College Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.

Int J Mol Sci ; 24(19)2023 Sep 29.

Article em En | MEDLINE | ID: mdl-37834184

Assuntos

Doenças Autoimunes; DNA; Imunidade Inata; Nucleotidiltransferases; DNA/imunologia; Imunidade Inata/genética; Nucleotidiltransferases/metabolismo; Transdução de Sinais/genética; Humanos

Palavras-chave

DNases; autoimmune diseases; cGAS; mitosis; self-DNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / DNA / Imunidade Inata / Nucleotidiltransferases Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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