Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease.

Wang, Xueting; Xie, Yuqi; Chen, Guijuan; Lu, Yapeng; Wang, Dan; Zhu, Li

Wang, Xueting; Xie, Yuqi; Chen, Guijuan; Lu, Yapeng; Wang, Dan; Zhu, Li.

Afiliação

Wang X; Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, No. 9, Seyuan Road, Chongchuan District, Nantong, 226009, Jiangsu, China. wangxueting@ntu.edu.cn.
Xie Y; Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, No. 9, Seyuan Road, Chongchuan District, Nantong, 226009, Jiangsu, China.
Chen G; Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, No. 9, Seyuan Road, Chongchuan District, Nantong, 226009, Jiangsu, China.
Lu Y; Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, No. 9, Seyuan Road, Chongchuan District, Nantong, 226009, Jiangsu, China.
Wang D; Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, No. 9, Seyuan Road, Chongchuan District, Nantong, 226009, Jiangsu, China.
Zhu L; Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, No. 9, Seyuan Road, Chongchuan District, Nantong, 226009, Jiangsu, China. zhulizhou@ntu.edu.cn.

J Neuroinflammation ; 20(1): 240, 2023 Oct 20.

Article em En | MEDLINE | ID: mdl-37864249

Assuntos

Doença de Alzheimer; Peptídeos beta-Amiloides; Animais; Humanos; Lactente; Camundongos; Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/toxicidade; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Autofagia/fisiologia; Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos/metabolismo; Modelos Animais de Doenças; Camundongos Transgênicos

Palavras-chave

Alzheimer's disease; Autophagy; Beta-amyloid degradation; Plaque-associated microglia; Transcription factor EB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Doença de Alzheimer Limite: Animals / Humans / Infant Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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