Management of transfusion-dependent ß-thalassemia (TDT): Expert insights and practical overview from the Middle East.
Blood Rev
; 63: 101138, 2024 01.
Article
em En
| MEDLINE
| ID: mdl-37867006
ABSTRACT
ß-Thalassemia is one of the most common monogenetic diseases worldwide, with a particularly high prevalence in the Middle East region. As such, we have developed long-standing experience with disease management and devising solutions to address challenges attributed to resource limitations. The region has also participated in the majority of clinical trials and development programs of iron chelators and more novel ineffective erythropoiesis-targeted therapy. In this review, we provide a practical overview of management for patients with transfusion-dependent ß-thalassemia, primarily driven by such experiences, with the aim of transferring knowledge to colleagues in other regions facing similar challenges.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talassemia
/
Talassemia beta
/
Sobrecarga de Ferro
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article