Synthesis of Cross-Chain Bridging Cryptands and Induction of Molecular Chirality.
Org Lett
; 25(50): 8959-8964, 2023 Dec 22.
Article
em En
| MEDLINE
| ID: mdl-37871274
ABSTRACT
In this study, we synthesized two cryptands featuring entangled tri- and tetra(ethylene glycol) linkers. The cryptand bearing short linkers was chiral without any asymmetric carbon atoms. After chiral high-performance liquid chromatography was used to separate the enantiomers, the absolute configuration of each cryptand was determined through single-crystal X-ray and circular dichroism analyses. The racemization of the cryptand possessing long linkers proceeded at room temperature.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article