The relationship between decline rate of residual renal function in the first year and mortality in peritoneal dialysis patients.
Ther Apher Dial
; 28(2): 255-264, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-37873689
ABSTRACT
INTRODUCTION:
To assess the relationship between the rate of residual renal function (RRF) decline in the first year and all-cause and cardiovascular mortality in peritoneal dialysis (PD) patients.METHODS:
Incident PD patients were divided into two groups by the corresponding RRF decline value, when hazard ratio (HR) = 1 was found by the restricted cubic spline. The associations of rate of decline of RRF in the first year with mortality were evaluated.RESULTS:
Of 497 PD patients, 122 patients died. After adjusting for confounding factors, patients in fast-decline group had a significant increase risk of all-cause and cardiovascular mortality (HR 1.97 and 2.09, respectively). Each 0.1-mL/min/1.73 m2 /month decrease in RRF in the first year of PD was associated with a 19% and 20% higher risk of all-cause and cardiovascular mortality, respectively.CONCLUSIONS:
Faster decline of RRF in the first year was independently associated with all-cause and cardiovascular mortality in PD patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
/
Diálise Peritoneal
/
Falência Renal Crônica
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article