Identification of &#945;-amanitin effector proteins in hepatocytes by limited proteolysis-coupled mass spectrometry.

Kim, Doeun; Lee, Min Seo; Kim, Nam Doo; Lee, Sangkyu; Lee, Hye Suk

Identification of α-amanitin effector proteins in hepatocytes by limited proteolysis-coupled mass spectrometry.

Kim, Doeun; Lee, Min Seo; Kim, Nam Doo; Lee, Sangkyu; Lee, Hye Suk.

Afiliação

Kim D; College of Pharmacy, Kyungpook National University, Daegu, 41566, Republic of Korea.
Lee MS; BK21 Four-sponsored Advanced Program for SmartPharma Leaders, College of Pharmacy, The Catholic University of Korea, Bucheon, 14662, Republic of Korea.
Kim ND; Voronoibio Inc., Incheon, 21984, Republic of Korea.
Lee S; School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: sangkyu@skku.edu.
Lee HS; BK21 Four-sponsored Advanced Program for SmartPharma Leaders, College of Pharmacy, The Catholic University of Korea, Bucheon, 14662, Republic of Korea. Electronic address: sianalee@catholic.ac.kr.

Chem Biol Interact ; 386: 110778, 2023 Dec 01.

Article em En | MEDLINE | ID: mdl-37879594

Assuntos

Alfa-Amanitina; Hepatócitos; Humanos; Camundongos; Animais; Alfa-Amanitina/metabolismo; Alfa-Amanitina/toxicidade; Proteólise; Simulação de Acoplamento Molecular; Hepatócitos/metabolismo; Espectrometria de Massas

Palavras-chave

Acute liver failure; Alpha-amanitin; Limited proteolysis-coupled mass spectrometry; Spliceosome; Toxic mushroom

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Alfa-Amanitina Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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