The parapoxvirus Orf virus inhibits dsDNA-mediated type I IFN expression via STING-dependent and STING-independent signalling pathways.

AlDaif, Basheer A; Mercer, Andrew A; Fleming, Stephen B

AlDaif, Basheer A; Mercer, Andrew A; Fleming, Stephen B.

Afiliação

AlDaif BA; Virus Research Unit, Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Mercer AA; Virus Research Unit, Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Fleming SB; Virus Research Unit, Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

J Gen Virol ; 104(10)2023 10.

Article em En | MEDLINE | ID: mdl-37882657

Assuntos

Interferon Tipo I; Proteínas de Membrana; Vírus do Orf; Humanos; DNA; Células HEK293; Vírus do Orf/genética; Proteínas de Membrana/genética; Transdução de Sinais

Palavras-chave

DNA sensors; ORFV; STING; immune modulation; interferon-beta; poxvirus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus do Orf / Interferon Tipo I / Proteínas de Membrana Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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