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Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation.
Lin, Lin; DeMartino, Jeff; Wang, Daisong; van Son, Gijs J F; van der Linden, Reinier; Begthel, Harry; Korving, Jeroen; Andersson-Rolf, Amanda; van den Brink, Stieneke; Lopez-Iglesias, Carmen; van de Wetering, Willine J; Balwierz, Aleksandra; Margaritis, Thanasis; van de Wetering, Marc; Peters, Peter J; Drost, Jarno; van Es, Johan H; Clevers, Hans.
Afiliação
  • Lin L; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
  • DeMartino J; Oncode Institute, Utrecht, Netherlands.
  • Wang D; Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands.
  • van Son GJF; Oncode Institute, Utrecht, Netherlands.
  • van der Linden R; Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands.
  • Begthel H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
  • Korving J; Oncode Institute, Utrecht, Netherlands.
  • Andersson-Rolf A; Oncode Institute, Utrecht, Netherlands.
  • van den Brink S; Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands.
  • Lopez-Iglesias C; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
  • van de Wetering WJ; Oncode Institute, Utrecht, Netherlands.
  • Balwierz A; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
  • Margaritis T; Oncode Institute, Utrecht, Netherlands.
  • van de Wetering M; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
  • Peters PJ; Oncode Institute, Utrecht, Netherlands.
  • Drost J; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
  • van Es JH; Oncode Institute, Utrecht, Netherlands.
  • Clevers H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, Netherlands.
Science ; 382(6669): 451-458, 2023 10 27.
Article em En | MEDLINE | ID: mdl-37883554
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Regulação da Expressão Gênica / Dedos de Zinco / Linhagem da Célula / Células Enteroendócrinas / Sistemas CRISPR-Cas Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Regulação da Expressão Gênica / Dedos de Zinco / Linhagem da Célula / Células Enteroendócrinas / Sistemas CRISPR-Cas Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article