TNF-&#945; Mediated the Disruption of Hepatic Tight Junction Expression in Blood-Biliary Barrier of Colitis via Downregulating PI3K/AKT Signaling Pathway.

Jiang, Xian-Sen; Fu, Bi-le; Yang, Xin-Xin; Qin, Hong-Yan

TNF-α Mediated the Disruption of Hepatic Tight Junction Expression in Blood-Biliary Barrier of Colitis via Downregulating PI3K/AKT Signaling Pathway.

Jiang, Xian-Sen; Fu, Bi-le; Yang, Xin-Xin; Qin, Hong-Yan.

Afiliação

Jiang XS; The First Clinical Medical College, Lanzhou University.
Fu BL; The First Clinical Medical College, Lanzhou University.
Yang XX; College of Pharmacy, Lanzhou University.
Qin HY; The First Clinical Medical College, Lanzhou University.

Biol Pharm Bull ; 46(12): 1769-1777, 2023 Dec 01.

Article em En | MEDLINE | ID: mdl-37899248

Assuntos

Colestase Intra-Hepática; Colestase; Colite; Ratos; Animais; Fator de Necrose Tumoral alfa; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Junções Íntimas/metabolismo; Colite/patologia; Transdução de Sinais; Proteínas de Junções Íntimas/metabolismo

Palavras-chave

bloodbiliary barrier; cholestasis; colitis; tight junction; tumor necrosis factor alpha

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colestase / Colestase Intra-Hepática / Colite Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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