Photoredox Metal-Free Synthesis of Unnatural ß-Silyl-α-Amino Acids via Hydrosilylation.
Chem Asian J
; 18(24): e202300805, 2023 Dec 14.
Article
em En
| MEDLINE
| ID: mdl-37906443
ABSTRACT
An efficient, practical and metal-free methodology for the synthesis of ß-silyl-α-amino acid motifs via photoredox and hydrogen atom transfer (HAT) process is described. This protocol enables the direct hydrosilylation of dehydroalanine derivatives and tolerates a wide array of functional groups and synthetic handles, leading to valuable ß-silyl-α-amino acids with moderate to good yields.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article