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A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer's disease.
Aron, Liviu; Qiu, Chenxi; Ngian, Zhen Kai; Liang, Marianna; Drake, Derek; Choi, Jaejoon; Fernandez, Marty A; Roche, Perle; Bunting, Emma L; Lacey, Ella K; Hamplova, Sara E; Yuan, Monlan; Wolfe, Michael S; Bennett, David A; Lee, Eunjung A; Yankner, Bruce A.
Afiliação
  • Aron L; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Qiu C; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Ngian ZK; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Liang M; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Drake D; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Choi J; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Fernandez MA; Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
  • Roche P; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Bunting EL; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Lacey EK; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Hamplova SE; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Yuan M; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
  • Wolfe MS; Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
  • Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL60612, USA.
  • Lee EA; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Yankner BA; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA. bruce_yankner@hms.harvard.edu.
Nat Commun ; 14(1): 7030, 2023 11 02.
Article em En | MEDLINE | ID: mdl-37919281

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article