Asymmetric Hydrogenations of Acyclic α,ß-Unsaturated Ketones with Chiral Frustrated Lewis Pairs (FLPs).
J Org Chem
; 88(22): 16038-16042, 2023 Nov 17.
Article
em En
| MEDLINE
| ID: mdl-37935680
ABSTRACT
In this paper, we demonstrate a metal-free asymmetric hydrogenation of acyclic α,ß-unsaturated ketones under the catalysis of a frustrated Lewis pair (FLP) comprising chiral oxazoline and achiral borane. A wide range of optically active α-substituted ketones were furnished in high yields with 26-85% ee's.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article