Your browser doesn't support javascript.
loading
Flavonoids: the use in mental health and related diseases.
Nicolucci, Camilla; Padovani, Milena; Rodrigues, Fernanda de Castro; Fritsch, Laura Nagy; Santos, Ana Cristina; Priolli, Denise Gonçalves; Sciani, Juliana M.
Afiliação
  • Nicolucci C; Medical School, São Francisco University, Bragança Paulista, São Paulo, Brazil.
  • Padovani M; Postgraduate Program in Health Sciences, Bragança Paulista, São Paulo, Brazil.
  • Rodrigues FC; Medical School, São Francisco University, Bragança Paulista, São Paulo, Brazil.
  • Fritsch LN; Psychiatry Medical Residency Program, São Francisco University Hospital, Bragança Paulista, São Paulo, Brazil.
  • Santos AC; Psychiatry Medical Residency Program, São Francisco University Hospital, Bragança Paulista, São Paulo, Brazil.
  • Priolli DG; Institute of Biophysics of University of Coimbra, Coimbra, Portugal.
  • Sciani JM; Institute for Clinical and Biomedical Research (iCBR/Cibb), University of Coimbra, Coimbra, Portugal.
Nat Prod Res ; : 1-11, 2023 Nov 10.
Article em En | MEDLINE | ID: mdl-37948603
ABSTRACT
Given the current increase in mental and neurological disorders, there is an urgent need to develop alternative treatments for patients. Flavonoids exhibit diverse biological activities, including antioxidant, anti-inflammatory and neuroprotective, and has been considered potential therapies for central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, drug addiction, and stroke. Studies have shown that flavonoids protect neurons from oxidative stress, reduce inflammation, improve brain blood flow and enhance cognitive function. Moreover, its modulation of neurotransmission, such as GABAergic, dopaminergic, serotoninergic, and noradrenergic, has been studied for the treatment of mental disorders that require sedative effects, antidepressants, sleep inducers and anxiety reduction. Although more research is needed to fully understand the mechanisms and potential benefits of these compounds, the use of flavonoids for neurological diseases is a promising avenue for future research and development. This review focuses on major flavonoid subclasses and their applications in central nervous system disorders.
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article