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Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery.
Novotná, Katerina; Tenora, Lukás; Prchalová, Eva; Paule, James; Alt, Jesse; Veeravalli, Vijay; Lam, Jenny; Wu, Ying; Snajdr, Ivan; Gori, Sadakatali; Mettu, Vijaya Saradhi; Tsukamoto, Takashi; Majer, Pavel; Slusher, Barbara S; Rais, Rana.
Afiliação
  • Novotná K; Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague 160 00, Czech Republic.
  • Tenora L; Department of Organic Chemistry, Faculty of Science, Charles University, Prague 128 00, Czech Republic.
  • Prchalová E; Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague 160 00, Czech Republic.
  • Paule J; Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague 160 00, Czech Republic.
  • Gori S; Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague 160 00, Czech Republic.
  • Slusher BS; Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague 160 00, Czech Republic.
J Med Chem ; 66(22): 15493-15510, 2023 11 23.
Article em En | MEDLINE | ID: mdl-37949450
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article