Development and validation of a multiplex HPLC-MS/MS assay for the monitoring of JAK inhibitors in patient plasma.

Tachet, Jérémie; Versace, François; Mercier, Thomas; Buclin, Thierry; Decosterd, Laurent A; Choong, Eva; Girardin, François R

Tachet, Jérémie; Versace, François; Mercier, Thomas; Buclin, Thierry; Decosterd, Laurent A; Choong, Eva; Girardin, François R.

Afiliação

Tachet J; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Versace F; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Mercier T; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Buclin T; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Decosterd LA; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Choong E; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Girardin FR; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland. Electronic address: francois.girardin@chuv.ch.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1230: 123917, 2023 Nov 15.

Article em En | MEDLINE | ID: mdl-37956468

Assuntos

Inibidores de Janus Quinases; Espectrometria de Massas em Tandem; Humanos; Cromatografia Líquida de Alta Pressão/métodos; Espectrometria de Massas em Tandem/métodos; Estudos Prospectivos; Monitoramento de Medicamentos/métodos; Reprodutibilidade dos Testes

Palavras-chave

Immunosuppressants; Inflammatory diseases; JAK inhibitors; LC-MS/MS; Targeted therapy; Therapeutic Drug Monitoring

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Inibidores de Janus Quinases Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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